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在發展中求生存，不斷完善，以良好信譽和科學的管理促進企業迅速發展We have used a design of experiments （DOE） approach to optimise rapidly a set of microwave
assisted conditions for the Petasis reaction. The optimal conditions involved the microwave
heating of the reaction components in dichloromethane （1M concentration） at120℃ for
10 min in a focussed microwave （CEM Explorer）. These conditions were successfully applied
to a range of Petasis reactions employing either glyoxylic acid or salicylaldehyde as the carbonyl
component along with a number of aryl/heteroaryl boronic acids and amine components.
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